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I was able to get from league 4 to 2, but the other players in league 2 have 3 to 4 times the health as me and mostly mythic cards.  Seems like huge jump in difficulty from league 3 to 2.  I'm level 38 with almost 800k health.

Me too! It's ridiculous!!
I won every game in league 4 (+36),
only lost two in league 3(+46,-2),
then have only won 3 out of 30 in league 2.
Players  generally have a minimum of 2.5M and 5 mythics,
and hit first, giving you zero chance of winning.
I'd hate to think what League 1 (DL) is like now!!


Same.