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I played the game once myself, and then played it again using the walkthrough. However, the game status shows that I still haven't read around 1800 language blocks.(15563/17388) So... we are expected to miss around 10% of the content when using the walkthrough?  Maybe there could be a more detailed walkthrough like that of "once in a lifetime". I'd like to find out the missing content even if they do not belong to the "best" route. 

I don't think you missed any contents. These missing things are probably just dialogues that kicks you from paths. So unless you wants to see them, you don't need to worry about missing content.

If you don't want to miss ANYTHING, I'd suggest you check other options in the choice menus even if you end up choosing the one the walkthrough says. Some are pretty entertaining too.