I think it's experience/trial error, after playing it a bunch of times, I can get through most places no matter the RNG items. And I know what and when I can face any enemies then act accordingly (Avoid, run or fire a bunch of arrows at it).
Though I couldn't of beat it just now on hard mode without good RNG and lots of empty scrolls. But still the same applied through most of the game. Even then I think I only bled once or twice in the entire game through at least an arrow trap at the end.
But anyway... For me it's why I love this game - it's grueling and unforgiving, just like the atmosphere.
May be an easy/casual mode for those who aren't masochistic gamers like me? XD With say like 75% chance of getting something without the coin toss mechanic, a chance to get Book of Enlightenment from bookcases, start of the turn choreographed pending insta-kill attacks so people know when to run or guard, 100% Ancient book success etc..
I understand the unforgiving mechanics aren't for everyone, so instead of getting rid of what I feel is the heart and soul, you can just add another mode instead. I can also see another mode making it streamer friendly too - the only way I knew about this game was someone attempting to play it on YouTube.