No, but you can only enter when your quest requires it. What quest are you on?
Oh yeah! At 20:00 teacher Mia goes home and she locks her office until the next day, so you can no longer enter her office or see her. At the moment there is no way to enter at those hours.
I think that, even so, currently you can enter her office because I forgot to block it from 20:00. It will be fixed from the next update.