I ended up mostly using the primary sword for killing the enemies, since the enemies were usually not visible until they are basically on top of me--making the projectile weapons difficult to use. BUT, beyond that I must say the overall difficulty is quite good. I made it through with one life left on my first try, and although getting one-shotted was frustrating at first, the fact that progress is saved helped a ton. As someone who also went with the random weapons approach, it was fun to try out all the options, and I really like the cool down icon in the top left--makes it very clear when I can/cannot attack.