first off i love this game its so fun (im #12 in the world with a time of 1:59.81) and the power ups make the game different every time. one idea for a buff is "random buff" and it just gives you any buff like four guns or like less rooms and it doesn't matter what you have so even if you have nothing then you could four guns.
glitches/bugs
the only 2 glitches/bugs i've seen is sometimes when you slide through room you'll get caught sometimes. the other glitch i know of is getting out of the map but im unsure of how to do it.