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Would like to know what Knots are. Also, the experiment "Dog Toy" implies that the dog is what does the Knotting, but then another experiment "Bitch" implies that a Knot is an entirely different mob that I haven't seen even though I've been on some decently high levels on Shack.

knots are when a dog nuts in the character.

check the death hound entry in the data section, it explains what it is