Basically my strategy. But I'd like to add a few notes:
* Know your enemy! You don't need a detailed codex of every attack every enemy can do, but knowing their general damage range and (of course) their special abilities is extremely helpful—in particular, it lets you determine when to pile on more Block dice to protect your precious HP and when to start attacking.
* Prioritize high-damage targets, unless they're way tankier than the little mooks (e.g. a blocking-beetle with a couple basic flies). The idea is to minimize the damage you take over the course of the fight; this rule of thumb does that pretty well.
* It's technically possible to get great dice on low floors—I've had The Holy (6*6 Attack die) below floor 5 a couple of times. But it's extremely rare—I try to avoid it.
* Mirror dice can be incredible, especially when paired with a 2* Boost.
* Prioritize upgrading Heavy dice, if you have them. Upgraded Heavy dice not only have a bigger effect when you play them, but stick around longer.
* If you get a purple fly, red archer, and axe beetle at once, don't be ashamed when you lose.