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Does not want to run on Mac. Each time it says "Application is not responding" and I eventually have to "force quit".

Is Gatekeeper enabled? After unsuccessfully opening the game, is there an option to click "Open anyway" in the Security settings in System Preferences?

It doesn't do anything. I open and it shows up in my dock as an active program, etc. However, it never actually opens and shortly thereafter, when I right click on the dock icon, it says "Application is not responding" and also gives the option to "Force Quit"

Have you checked the Security pane in System Preferences? It sounds like Gatekeeper is preventing the application from starting.