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I have the same problem. Running the exe from powershell gives the following error: 

.\big_trouble_in_outpost_31.exe
Traceback (most recent call last):
  File "big_trouble_in_outpost_31.py", line 893, in <module>
  File "zipextimporter.pyc", line 82, in load_module
  File "sdl2\__init__.pyc", line 2, in <module>
  File "zipextimporter.pyc", line 82, in load_module
  File "sdl2\dll.pyc", line 115, in <module>
ImportError: could not find any library for SDL2 (PYSDL2_DLL_PATH: unset)