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I'm running the itch.io PC app on Windows 10.

Ahh, the itch.io app is a manager that downloads and unzips it for you. I tested it here and it's working fine, it could be some bug on the app...

Try downloading it manually directly from the game's page instead.
If you don't know how to do it I can help you.

it just occurred to me, the PC version is not available for free (only Android with Ads is free) so the error may be related to the app not being able to access the files... if you did buy it, then try downloading manually!