So I'm about five-six passes in now. Semi-consistently getting to the hive (though it has awful performance). Some feedback, though;
DNA TYPES as a whole are unclear. What's the difference between base/volatile/fortified/etc.? Is there a risk of even "OK" installed DNA randomly mutating and eventually expiring?
Prism Transmitter Arm is really counterintuitive. The tooltip states 'Chance to Hack Robots', but that "chance" seems to be 100%. It also doesn't mention that it disables your standard melee functionality i.e. damaging enemies, meaning it's dead weight if you face a lot of Solus and few Prism.
Prickled Shell seems to reflect certain shots from all angles, particularly Prism turrets. Have not tested extensively though.
Sack Feet deleted Freya's thighs. Now how is she supposed to sit down?!
In other miscellaneous issues, I found a gun that I couldn't pick up (outside a tent, it triggered the Weapon Variants log entry but was completely impossible to interact with) and am generally seeing a lack of alternative weapons in general, even when searching for them; I'm finding maybe one per level at best, and it's kind of a pain when you get something like Rejected Arm so you can only use one-handed weapons (and with awful accuracy at that).
Aside from that, everything seems promising so far.