The problem is that they are extremely blurry, so it is very difficult to make the image come into focus, because the focused image is also blurry.
I'm in the same boat as you, and it's really disappointing to not be able to play this game. The only way I was able to make out the image in the screenshots was to scale down to 50% (effectively reduces the blur), and then slowly go back to 100%. But even then, at 100% scale it's really difficult to maintain because of the blurred pixels.
I don't get it. Why would you make the image so blurry? Even when you play the game at 640x480 the pixels are big and blurry.
Use nearest neighbour sampling please!