He won't let me take the mission, and then I got stuck there, maybe it's something super basic and the answer is right there, but I'm a bit silly sorry :(
That is certainly unusual!
Have you made enough restrain potions that you have it mastered? It may help to try that.
She should have explained how to make a strong restrain potion, but in case not, it's: Red Pulp first and fifth, Nut second and fourth, Earth Moss in third.
Try having seven of those and see if that adjusts things?