spoiler/theory
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I think it's preety obvious, but i haven't seen anyone talk about it. I believe tak the "reaserch" Murrow stole from the bat lady is conected to cole being the son of both marrow and hamish, it would explain why he was very "sick" When he was young and is smaller than most hyenas and why we never heard about his mother. I think the Spell/ritual was succesfull but it had lasting side effects on cole.