This looks really cool, love how you've managed to get the map layout to fit together with all these rectangular rooms. The art style looks great too.
Is there going to be an on screen map to aid with navigation? I imagine the perspective changes could become a little disorienting during play (some classic survival horror games had problems with this). The Consuming Shadow does something with a similar style (which you may already know about as you've referenced another of Yahtzee's games) but with the perspective remaining consistent, because it's just layers of corridor rooms.
I can see the way you've done it allows for much more complex and varied maps though, which could let you get a lot more variety .