No offense taken, pardon me if I made it sound like I did.
I'm sadly not more knowledgable than those guides either – for instance, I'm sure you've tried this for the WSL thing as it's the first guide I found on the matter.
From the reports I have seen so far, VirtualBox ought to "just work"™ with most issues regarding Guix on VirtualBox being really minor like not being able to fullscreen the VM (that shouldn't matter as long as you can reserve 1280x720 for the game window). There are even some guides on setting it up (technically the latter is a Vagrantfile + deco, but it should help you set it up either way), though I can't guarantee for quality as they use ancient versions of Guix or at least ancient language.
There seems to also exist QEMU for Windows, which sounds like a reasonable idea because QEMU images for Guix exist, but getting from there to "ooh, I can finally play the game" is perhaps even harder.
Note that with both of those you'll likely take a performance hit, but it shouldn't be so bad as to make the novel unplayable.
As far as "reading the story" is concerned, you do have the full source code, so if all else fails, you can at least read the dialogue from there. I don't think a transcript would be particularly useful, but if you feel differently, do not hesitate to suggest so.