I picked up the first available object in the game (a cup) and I wasn't able to make it the "active" item from the inventory screen. I thought maybe it was something about that object -- there are a few other disposable cups in the game, and maybe all you intended for me to do with them is drop them. However, when I finally found a cabinet key (presumably important), the game wouldn't let me use that item either. Maybe that is your intention, but if this is intended to be an escape-the-room game and not some kind of artful experiment, you might want to make sure that players can use a key on a lock.
Also, this is not a deal-breaker for me, but you are expecting players of an essentially casual game genre to learn a LOT of function-specific key bindings here. Classic escape games are point-and-click, and that ease-of-use is part of the appeal. Obviously, you are putting a 3D, FPS (first-person solver?) gloss on it, which is great! Absolutely, do that! But I would like this game a lot more if my mouse buttons assumed the functionality you currently have variously assigned to the keys E, V, F, and Q. Everyone knows WASD, and based on the design, I can see how you would want a function key to open and close the inventory. But asking players to also remember that viewing something requires a different button than picking something up, which requires a different button than using an item--it all seems needlessly complicated, and it kind of sucks to play when it could be so much simpler. I quit the game after exploring a bit, solving one puzzle, and finding one unusable key, but even in those few minutes I found myself pulling up the "help" screen multiple times just to remember which button you want me to use for what. I mean, when I look at the key in my inventory, there is a tooltip that tells me which button will drop the item, but not which button will let me use the item, which seems like an oversight.
Anyway, I hope I don't sound like too much of a jerk... I really do appreciate what you're trying to do here, and I will still be excited to play this game when it becomes functional for me.
PS: I'll attach a screenshot of this, but on the left side of the room, in the filing cabinets between the two bookshelves, it's possible to read the document in the top-right drawer (the "CODE = ABCDD" note) even though the drawer is still locked. Seems like a glitch.