Oh, I just meant difficulty overall. I think games like Wizardry are better suited for one overall difficulty that the game is developed around. I do like the sound of adding more depth to the formula, and I would love to see what you might do with it.
Although difficulty settings does sound like an interesting option, especially if some rules change. You know how certain enemies can 1hit kill PC's with a behead attack? Maybe have that as a rule for the base game, but easier difficulties remove it. Or maybe you get different, more harder encounters on harder difficulties, adding a certain challenge to people proficient in the genre.
It's an interesting thought, to be sure. Though I don't know if it's worth the effort!