Things I've encountered:
Going to school and changing upon arrival while its raining has it raining in the locker room. I do not know if it has to do with cheats being enabled: max skills and enable all clothes are turned on.
When you move from the gym to locker room and shower, it puts you back into the gym immediately after with whatever outfit you had on.
If you talk to Dr. Nikolas and change appearances right after the option is made available, you are taken through the Dr. Brooker dialogue again.