there could be similar xdelta tools on mac but i do not own one so i am unaware of them. but the patched iso should work fine on mac, you just may need to use a windows pc to build it
Adding on to this, if you don't have a Windows PC for whatever reason you can always download a windows 10 image from Microsoft's website and just fire up a VM for it, Build the patched iso, and transfer it out through a shared folder.