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(+1)

I found that you can open terminal and run

sudo chmod -R 755 Path\ to\ app\ file.app

and then just run the game normally

(+1)

I have seen this with some Itch games. Somehow the permissions don’t get set right, so (for the less technically literate) this command just tells your computer that it’s a program you can run. For the path, just drag the app onto your Terminal window.