Set your printer to print in booklet format, it's going to place the pages in the right order and it turn the sheets automatically if your printer has that option, if not it will print one side of the sheet first and then you will have to put the paper back to print on the other side, follow the instructions of your printer and you will be fine! I would suggest to make a test first to be careful, print a black white fast draft to learn how to do it then you print in high quality color.
Then fold the sheets, staple them in the back and your home made zine is done!