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I'm having the same issue, and it's on my laptop so it's definitely not tied to my mouse specifically (which is a Logitech G600, for what it's worth) since it's happening even when that's not plugged in. Really unfortunate that it's happening; some friends and I were enjoying the game but couldn't progress since we couldn't look down to examine things

That's ever so odd. I didn't really change anything from the way Unreal handles mouse movement by default. If either of you have a USB gamepad, try using that.

If either of you are still interested, the new update crushes that mouse bug that made it unplayable.