Working on my isometric project I'm now realizing a challenge with things hiding behind taller structures. I'm thinking about two ways to solve it in the future: one is to being able to rotate the map, the other is to give a transparent view to the mouse pointer so moving the mouse over a tall building would make it, or the mouse area semi transparent. For my game it's not super important to see what's happening behind my buildings, but for you, placing the belts and building the tiles it's much more important, so perhaps the 2d top down approach is not a bad idea, it worked rather well for "Factorio". I would try the isometric view but keep an open mind that it might need to be scraped at the end.