I'm still figuring out where all the weapons are meant to be used. But it seems to work if I can hit them with an explosive then fire a machine gun.
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Bloatsprites: Get them close and
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them up with flamethrowers or something that burns, then if you like going for the nest, go in and spam anything that burns. If you do this, the bloatflies spawn directly in front of you, so use your strongest melee to kill them off and probably use it on the nest as well if you run out of fire >:3