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Thanks for giving it a try. Give each Ribosome two Glycolysis (each with a Fermenter). One Glucose transporter can feed both.  I updated the tutorial and adjusted some of the throughput alerts to be more clear.

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I think I figured out my problem, the Lipid synthase Breaks the NAD+ loop, as it's the one pyruvite consumer that doesn't return NAD+.  Given that it's not actually necessary with enough ATP generation, things went better without it.