You can actually get multiple endings. Once you've permalocked an outfit and seen the ending, return home and ask your visitor for acid, then go take a shower with it (but be sure to remove any other items you want to keep!) The permalocked bindings will be deleted, freeing you to continue pursuing other endings. Note that if you remove these "ending sets" you can collect duplicates, allowing you to use them to your advantage.
There's an option to disable the minigames, replacing them with a timer that is affected by your status; i.e. having your hands bound will make removing most stuff take a bit longer, just as an example. There are also quite a few clothing items to collect that don't bind you so you can fashion it up if you so choose.
Note that each enemy can only bind specified locations on your body so if you're already wearing bindings in all applicable slots, a given enemy type will completely ignore you, even if you slap it. This allows you to purposely wear some bindings that don't hinder you as much in order to avoid more inconvenient ones. Of particular note, arm bindings that keep your arms in front of you instead of behind you can permit you to slap even when bound.