Plays out really well, nice game. My only problem was, self targeting skills not working, like iceman's feeze or serum for beast. When try to target self your unit gets deselected.
I finished the game in all difficulties :D
It started well, I died at first once, then finished all difficulties without a game over. More bosses would probably cought me off guard and may have caused a few more game overs.
After getting used to which enemy does what, only thing that caused suprises was those guard bots that can push you, those can push you to other enemies range into an unexpected damages.
Otherwise plays out well and balanced, in none of the plays I get an overpowered unit. And the civilian or police missons also felt pretty fair.