A really fun and creative idea, but a bit too difficult. I really liked how chaotic and complex it got, though the timers were (for my skill level) too short and gave me no time to think, so I found myself constantly just focusing on the life timer and button mashing to hopefully get the required score. I think having a mode where it is turn-based (or just a slower one) could allow a lot more less skilled players to play the game.
The art and sounds were simple and effective, I don't have much to comment on that, I liked it. Some background music and maybe timer sounds (when they're about to run out, to add to the chaos) could lift the game even higher.