Acts 1 and 2 of Minotaur Hotel were written over 2 or so years when we were working under a philosophy of "Superserve your first audience" -- in our case we were working with gay men in mind. It was not a bad idea, I think it did a lot to establish our readership.
We tried to include female characters where we could (and the Hinterlands, in particular, had serious thematic reasons for it, I consider it very core to it in fact), but nonetheless there is no on-screen female character as part of the main cast.
The stretch of content we are walking into right now, Act 3, is something we've worked while informed by the reality that now we already have a loyal audience, and, if I may speak frankly, the cast of men we provide is already satisfactory in number, depth and quality. The "superserve your first audience" advice, while still important, is no longer the first on our list. Moreover, Minotaur Hotel has a foot firmly planted on literary fiction -- and if having a female character is what the story needs to explore its themes, that's what must be done.
In short: expect a more diverse cast going forward. We plan on introducing a female character, most likely in Chapter 21, who'll be part of the main cast. She's one of the characters I'm most excited about, I've been working on her concept for years. There'll also be other female characters, though they won't have as much screen time, and we're also introducing a trans character soon in Luke's overhauled hangouts.
There is another reason I could offer as to why there're no female characters, and it's actually the most direct and simplest, but it'd also be a bit of a spoiler. I can say it if you want but it's something people can already make out from what's already in the game.