The game loop was very unique and interesting. At one point, I felt like the plague just kept progressing and no matter what cures I tried, I wasn't able to get ahead of it, like there is no win condition. But maybe that was the point of the game - that he was supposed to die, similar to how it was to live with plague during that period? Which if that's the case, you captured the experience perfectly! What I found interesting was how I felt compelled to do everything in my power to keep the patient alive, despite knowing he couldn't be saved...
I loved the sound design (one of the top ones I've seen this jam) and the story was captivating - the plague genuinely gave me the ick; something about those sores on his back started getting gross at one point lol. The permanent plagues didn't really feel permanent because I was able to excise them - not sure if that was a bug. Nonetheless, this was a fantastic entry!