Oh one thing that bothers me, as playing a mage: I do have now to click now every time on the runed spell and target the enemy again? That worked else before, you could like spam magic missile.
Yes, that's a change between the gamepad and the mouse controls that is a little more like the original game when playing with the mouse. I don't think it's too onerous, and it puts the "randomness" on the cast click rather than on the targeting click.