The next update adds a passive weight loss home upgrade, but I might expand on the Metabolic Regression Device & allow the player to use it, or something similar, beyond escaping the facility. That'll probably be a reward from the new Dizzy's progression systems I'll add in the London update.
I want to include more detailed weight descriptions in the sex update. I'm not too far away from starting work on that now that I've nearly finished Jobs & Home. I'll add lots more interactions with girls whilst they're naked, where their cellulite & stretch marks will be fully visible.