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You need the key first, and I'm pretty sure you need to have the labratory unlocked (by running past countryside)

Do yosuke's quest

- attend Friday party

- meet Yosuke at night day after party 

- get the thing for him from science student (random event during the day)

- attend 2nd party 

- meet up with yosuke again to give him the thing, he will ask for pizza 

- cook pizza in the kitchen 

- meet up with yosuke, he will point you to kan's room

- attend party to break into Kan's room to get lab key

- run until you reach lab