I got to play two sessions of this and it was incredible. I was a Casualty in CONSUME. Part of my body was remade of our dead Alpha friend.
One thing that came up was a confusion over the sticklerness of "when you gain Void". Does "grow a new void asset" count as gaining Void? Handler ruled that thematically it counts, and I was fine with that, so we were marking off Casualty's body parts more often, once from defeat and once from something else that added a void asset. But there were quite a few times I was growing void assets without the keyword "gain" and I wasn't sure how my character could last a third session if it counted. But that might also be on-point for a Casualty.
We also ruled that Handler was "regular people". That was a good ending.