Once I unlocked the first mutation (Sunny), in the following runs I could no longer place anything - not even the very first 25-seed flower. At first I thought maybe it would only affect one run so I waited to lose, unlocked another mutation (the bottom right one) and start another run. But I still couldn't place anything. I had 75 seeds at the start ;-;
Still, I got the general concept. A very solid tower-defense game if I didn't encounter the bug (no pun intended). I liked that you literally start stronger so that you could use your new shiny flower earlier~