I installed this game on my external drive on windows 10. I don't think it likes that very much...it keeps randomly closing on me! No error message or anything. I did make a little fish/worm thing and swam it around a bit though.
At first I thought maybe it was because I was spamming right click to get rid of muscles that I'd misplaced, and somehow accidentally exited the game that way, but then it closed on me abruptly again while I was trying to decide which mouth to put on my creature and I wasn't clicking anything.