I definitely wouldn't recommend using an image editor to make new sprite sheets. That's that waste of resources i was talking about. Not to mention time and energy better spent elsewhere. Just load the sprite sheet and use your animation editor to choose which frame is showing.
I don't know what game engine you're using, but the Sprite Customizer was made in godot with this free plug-in (and it doesn't require a hundred different sprite sheets to run all the animations): https://feendrache.itch.io/manaseed-character-animator-for-godot