Wow, just wow. I am absolutely amazed by this game. It totally surpassed my expectations. At first when I saw the video I didn't think it would be this good, but playing it completely changed my opinion. The idea is brilliant and I loved the item synergy system. I was really invested in the game trying to achieve the best item combos!
I also want to congratulate the game's artist as I loved the art and music!
If I had to suggest something, I would recommend using different keys for stacking and dropping boxes / items as it can be somewhat difficult to organize everything when there are a lot of things.
All in all, congratulations on the game. If you decide to continue developing it I can already see it becoming an amazing game as it has huge potential!