This looks like it's being prevented from saving which could be an antivirus or permissions issue.
First try to launch the game directly as admin and not from the itch.io app and see if that helps.
If not, please see if any of the below are helpful to try and troubleshoot:
https://steamcommunity.com/app/698780/discussions/0/3182216552771027786/?l=english
https://steamcommunity.com/app/344770/discussions/0/1620599015869121835/