This is some real impressive work!
You've managed to create a whole bunch of different units and enemies, and the roguelike-factor works really well!
The only big issue I see right now is that you can get upgrade cards for buildings, without being able to produce the resources you need to build it. Initially I assumed I'd unlock the resource production buildings when I unlock the unit building, so when I then tried to build anything from that chain, I was a bit confused why it didn't work. But by run 2 I got how it worked, and with some gears I made it pretty far on run 3!