I really like how the immune system fights back, and will fight back more at higher temperatures! That's a really creative idea. Another thing that could maybe help with gameplay experience is incorporating subtle animations or other UI elements to help direct the player. For example, it was a bit difficult to understand how the immune system fights back, and what the number at the top left was. I could kinda just spam a bunch of organs and veins until things were working. But otherwise, this is a great take on the theme and I would love to see a post-jam version!