I have no clue what you are talking about.
Itch is a website. Virustotal is a website. You downloaded a file from Itch by using a webbrowser. You currently access Itch with a webbrowser and write comments.
So download the file that you suspect was malware with the webbrowser you currently use on the device you currently use and then upload it to virustotal. Then you will see what several scannes would have said about the file.
Or you can probably just use your current device and a usb cable and transfer the file for inspection. Or at least look how that file was named.
If I read correctly. you currently have a Meta Quest device that you think you cannot operate, because you think there is malware on it and are afraid when you power it up, someone on the internet will attack you.
You can always just go somehwere where there is no internet and power it up and try removing the files. Or if that fails, use the reset mechanisms that device is bound to have. I would suggest disabling internet access for the device in your router, but I fear that is above your technical ability, so doing it literally by foot is easier.
There is also bound to be support message boards for that Meta Quest thingy. The things you describe sound like very specific things that would only happen on that device. Just search for your specific problems or ask one of those ai chatbots. They are good at these things.