If you mark a room for deconstruction when you're out of money and the room is in need of repairs, and then you deconstruct the room, it breaks the construction / room system for the tower seemingly permanently. Easy way to replicate: start game skipping intro, build a meditation chamber, wait until it needs repairs due to lack of money, then mark for deconstruction and deconstruct room. The result will make it basically impossible for you to construct any new rooms or manage them properly. For example, here's the menu that comes up when i try to interact with this empty plot to assign some construction on the top floor of the tower:
