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Is it the windows version, or the mac version? I know the mac version has more issues than the windows one, a Tyrano dev said mac can just be a bit dodgy with some of the stuff Tyrano uses >.< Also, how long have you waited after clicking the exe? 

If it's the windows version and you've got plenty of free space on your drive, I don't really know what could be causing it to be unresponsive :( It's possible your PC might require some of the files that the Tyrano export tutorial said to delete. Cos the tutorial says to delete all the files in a certain folder, but if I do that, the game no longer opens on my PC! So that part of the tutorial is wrong >.< 

That's a complete guess though cos it runs alright on my PC and laptop as it is so it's hard for me to think of anything else. I can't send you the files at the moment, as I don't have my PC set up here, but I'll try to get it set up later tonight and I'll upload the files here to see if that makes any difference. Once they're here to download, just paste them into the game folder. I'll also make a post when I get time about known issues and possible fixes :3 I'm just busy with family stuff at the moment so can't do it right now. 

EDIT: I made this post. It includes the files I mentioned earlier, plus a few other suggestions:
https://melancholy-marionette.itch.io/solipsism-reigns/devlog/154575/known-issues-potential-fixes

As I said in the above post I linked, I've also asked for fix suggestions in the Tyrano support forum :3

Just wanted to let you know that I've now released a smaller version in the hope that it will run for anyone having issues launching the original larger version :3 I have no idea if it will work >.< haha, but other Tyranobuilder users have suggested to me that it's often a memory issue when it fails to launch on random devices, so I figured it was worth a shot!