I'm assuming your alright with spoilers. if not, spoiler free version is yes it changes something, but it doesn't cause any problems for us at the moment and just lets you side with her or another person, so choose whatever you feel is best in your heart.
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spoiler variant, the other person you can side with is Nameless and you can get more dialog with him + side with him over her. this has absolutely zero consequences at the moment but the other side also has zero consequences at the moment.