As an avid and long-time fan of Holmes, canon and many pastiches alike, I really enjoyed the concept and plot of this game. It's very apparently you put a lot of effort into this - the game's mechanics, systems, and design. As I'm playing on MacinCloud, it's disappointing that I was unable to hear any of the narration/sounds, I imagine it would have added even more to the experience. The only problems I noticed were small, some screen alignment stuff (loading screen and one of the clue's in Watson's Room was mostly hidden off the right edge) and the some things could be a bit hard to see due to the dark environments (although it also added to the ambiance), but it may have just been due to the simulator I'm using on MacinCloud.
Nice job!