Hello! :)
It works for most people :)
Are u using Windows ? if yes there is a ready to use Mame package available for download.. then use 'run.bat' to start the game.
Concerning emulators like Mame and FBNeo, DD1 is now officially supported so you'd better ask their forums / authors and/or maybe read some documentation.
It has also been reported that the game runs fine with Retroarch using Geolith core + NeoSD version of the game (doubledragon.neo)
In any case, you're welcome to join our discord channel and ask for help from our beloved followers ;-)
Hope that helps.