There's some the devs are aware of, I don't recall them knowing about the inventory glitch where most stuff in your inventory from previous saves disappears (loaded a sandbox save where I had the newest kerfur skin and the sandbox disintegrator in my inventory, so it doesn't delete ALL items)
By the by, pipebombs do not require extreme combat on. I know this because I didn't wanna turn it on when I fought [[a certain cat]] so I just spawned in a ton of them.